How to get from Prague to Brussels
A real 1-leg route: bus. Door to door 13h 20m, from €80.
We compared the ways to travel from Prague to Brussels. The most useful door-to-door route takes 13h 20m by bus with no transfer. The two cities are about 719 km apart in a straight line. The price and operators below come from a real route search.
This fare comes from a search on September 1, 2026 and has not been refreshed since. Run a live search for today's price.
Prague to Brussels: cheapest or fastest?
All from the same recent search. Pick a tab: the legs, the timing and the difference from the others all change with it.
- 1Prague → Brusselsbus
FlixBus·13h 20m
The best balance of price and time we found on this route.
How the trip from Prague to Brussels works
Start with a FlixBus bus from Prague to Brussels, about 13h 20m. In total it's roughly €80 over 13h 20m, direct, no transfers.
Along the way to Brussels
DeparturePrague
ArrivalBrusselsWhat Omio sells on this route
Omio's own lowest fares, one per mode. These are starting prices for the route in general, not for a date you picked, and they are refreshed once a day.
Omio last refreshed these on Thu, Sep 3
Who runs Prague to Brussels
On this route you travel with FlixBus; Routavio does not add a booking fee.
Prague to Brussels: common questions
How long does it take to get from Prague to Brussels?+−
The most useful route takes about 13h 20m by bus, with no transfer.
How far is Brussels from Prague?+−
About 719 km in a straight line. The real route on the ground or in the air is longer.
How much does Prague to Brussels cost?+−
The best price in our latest search was €80. The exact fare depends on your travel date.
Which operators run Prague to Brussels?+−
On this route you travel with FlixBus.
What is the cheapest way to get from Prague to Brussels?+−
Usually a flexible date, or leaving from a nearby airport. A live search puts every option for your dates side by side.
Can I book directly?+−
Yes. Routavio sends you straight to the operator or an independent third-party provider. We never add a booking fee. The final fare and availability are confirmed by that provider.
Where to next
Other ways people search Prague to Brussels
- how to get from Prague to Brussels
- Prague to Brussels travel time
- Prague to Brussels distance
- cheapest way from Prague to Brussels