
How to get from Manisa to Istanbul
Manisa to Istanbul is 301 km in a straight line.
On Routavio you can compare the ways from Manisa to Istanbul by price and travel time (route calculated on 10 October 2026).
- First bus at 07:00, last at 23:59
Compare the ways to get there. Then check them for your own date.
Route details last verified on 10 October 2026.
Start with the whole journey.
We compared the ways to travel from Manisa to Istanbul: bus. The two cities are about 301 km apart in a straight line. The operators below come from a real route search, last verified on 10 October 2026. Run a live search for current times and fares.
301 km
Manisa to Istanbul: cheapest or fastest?
Pick a tab: the legs, the timing and the difference from the others all change with it.
- 1Manisa → İstanbul Dudullubus
Metro Turizm·5h 15m
The best balance of price and time we found on this route.
Departures from Manisa to Istanbul
FlixBus publishes departures from 07:00 to 23:59.
| Operator | Departures a day | First | Last |
|---|---|---|---|
| FlixBusbus | · | 07:00 | 23:59 |
| Kamil Koçbus | 2 | 10:00 | 23:59 |
| Metro Turizmbus | · | · | · |
All departures FlixBus
- 07:00
- 10:00
- 20:59
- 23:59
All departures Kamil Koç
- 10:00
- 23:59
Departure times come from operator timetables and are local time at the origin. Where a row shows no times, we do not hold a published timetable for that operator. Times can change on holidays and at short notice; confirm with the operator before you travel.
Departure and arrival

Operators seen on these journeys
On this route you travel with Metro Turizm; Routavio does not add a booking fee.
How the trip from Manisa to Istanbul works
Routavio built this route from its own route data on 10 October 2026. Start with a Metro Turizm bus from Manisa to İstanbul Dudullu, about 5h 15m. In total it's roughly €22 over 5h 15m, direct, no transfers.
Where to stay
Stays in Istanbul on Booking.comRent a car
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Things to do in Istanbul
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Manisa to Istanbul: common questions
When is the first bus from Manisa to Istanbul?
The first bus with FlixBus leaves at 07:00 and the last at 23:59, according to the published timetable.
How far is Istanbul from Manisa?
About 301 km in a straight line. The real route on the ground or in the air is longer.
Which operators run Manisa to Istanbul?
According to Routavio's route data, on this route you travel with Metro Turizm.
What is the cheapest way to get from Manisa to Istanbul?
Routavio's comparison usually points to a flexible date, or leaving from a nearby airport. A live search puts every option for your dates side by side.
Can I book directly?
Yes. Routavio sends you straight to the operator or an independent third-party provider. We never add a booking fee. The final fare and availability are confirmed by that provider.
Other ways people search Manisa to Istanbul
- how to get from Manisa to Istanbul
- Manisa to Istanbul travel time
- Manisa to Istanbul distance
- cheapest way from Manisa to Istanbul
Sources and method
Routes are calculated by Routavio's multimodal engine from operator timetables and flight data. Durations come from timetables. The price here is our estimate, not a guarantee.
Operators: Metro Turizm
Route calculated: 10 Oct 2026