Start with the 09:30 flight from Istanbul to Eindhoven, about 3h. Transfer in Eindhoven, then take the 15:30 FlixBus bus on to Maastricht (1h 10m). Transfer in Maastricht, then take the 18:16 Arriva train on to Liège (10 min). You arrive in Liège around 18:26. In total it's roughly EUR 100 over 8h 56m, 2 transfers.
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Opens Omio — enter your date to compare trains and buses for this route; the price is finalised at checkout.
Fly into Eindhoven, then continue to Liège by bus (1h 10m) — routing via Eindhoven keeps the trip simple. Flight (3h) + Bus (FlixBus, 1h 10min) via Eindhoven + Train (Arriva, 10min) via Maastricht.