Start with the 13:40 Pegasus Airlines flight from Istanbul to Düsseldorf, about 3h 20m. Transfer in Düsseldorf, then take the 18:20 DB RE train on to Cologne (30 min). Transfer in Cologne Airport CGN, then take the 20:15 FlixBus bus on to Trier central (2h 15m). You arrive in Trier central around 22:30. In total it's roughly EUR 103 over 17h 22m, 3 transfers.
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Opens Omio — enter your date to compare trains and buses for this route; the price is finalised at checkout.
Fly into Düsseldorf, then continue to Trier central by train (30 min) — routing via Düsseldorf keeps the trip simple. Flight (PC, 3h 20min) + Train (DB RE, 30min) via Düsseldorf + Bus (FlixBus, 2h 15min) via Cologne Airport CGN.