Frankfurt → Milan

Start with the 07:30 FlixBus bus from Frankfurt to Kornwestheim Post Waypoint 2, about 3h 15m. Transfer in Kornwestheim Post Waypoint 2, then take the 11:15 FlixBus bus on to Kornwestheim Pre Waypoint (15 min). Transfer in Kornwestheim Pre Waypoint, then take the 13:00 FlixBus bus on to Stuttgart West (40 min). Transfer in Stuttgart West, then take the 15:30 FlixBus bus on to Stuttgart Airport Busterminal (25 min). Transfer in Stuttgart Airport Busterminal, then take the 17:45 (+1d) FlixBus bus on to Milan (7h 5m). You arrive in Milan around 00:50 (+1d). In total it's roughly EUR 90 over 27h 40m, 4 transfers.