Start with the 05:00 FlixBus bus from Bursa to Istanbul, about 1h 30m. Transfer in Istanbul, then take the 09:15 Pegasus Airlines flight on to Bratislava (2h 15m). Transfer in Bratislava, then take the 15:30 FlixBus bus on to Vienna (52 min). You arrive in Vienna around 16:22. In total it's roughly EUR 102 over 12h 25m, 2 transfers.
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Opens Omio — enter your date to compare trains and buses for this route; the price is finalised at checkout.
Fly into Bursa, then continue to Vienna Erdberg by bus (1h 30m) — routing via Bursa keeps the trip simple. Bus (FlixBus, 1h 30min) + Flight (PC, 2h 15min) via Istanbul + Bus (FlixBus, 52min) via Bratislava.