Start with the 10:55 Turkish Airlines flight from Istanbul to Brussels, about 3h 30m. Transfer in Brussels, then take the 17:45 FlixBus bus on to Amsterdam (2h 40m). Transfer in Amsterdam, then take the 21:57 Regional connection train on to Antwerp (1h 54m). You arrive in Antwerp around 23:51. In total it's roughly EUR 181 over 12h 56m, 2 transfers.
Turkish AirlinesKiwi opens sorted by price, cheapest first. Final fare is confirmed at checkout.
FlixBusOpens Omio — enter your date to compare trains and buses for this route; the price is finalised at checkout.
NS + metroOpens Omio — enter your date to compare trains and buses for this route; the price is finalised at checkout.
Fly into Brussels, then continue to Antwerp by bus (2h 40m) — routing via Brussels keeps the trip simple. Flight (Turkish Airlines, 3h 30min) + Bus (FlixBus, 2h 40min) via Brussels + Train (Regional connection, 1h 54min) via Amsterdam.