Start with the 08:40 AJet flight from Istanbul to Brussels, about 3h 35m. Transfer in Brussels, then take the 15:30 FlixBus bus on to Amsterdam (2h 40m). Transfer in Amsterdam, then take the 19:42 Regional connection train on to Antwerp (1h 54m). You arrive in Antwerp around 21:36. In total it's roughly EUR 125 over 12h 56m, 2 transfers.
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FlixBusOpens Omio — enter your date to compare trains and buses for this route; the price is finalised at checkout.
NS + metroOpens Omio — enter your date to compare trains and buses for this route; the price is finalised at checkout.
Fly into Brussels, then continue to Antwerp by bus (2h 40m) — routing via Brussels keeps the trip simple. Flight (VF, 3h 35min) + Bus (FlixBus, 2h 40min) via Brussels + Train (Regional connection, 1h 54min) via Amsterdam.