Start with the 07:00 FlixBus bus from Adana to İstanbul Dudullu, about 11h 25m. You arrive in İstanbul Dudullu around 18:25. In total it's roughly EUR 69 over 11h 25m, direct, no transfers.
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This route offers a cost-effective option at €69 for a 11-hour bus journey from Adana to Istanbul Dudullu via FlixBus, with no transfers required. While the synthetic schedule may lack real-time accuracy, the direct connection minimizes logistical complexity and avoids potential delays from transfers. Travelers prioritizing budget over time efficiency might favor this option, as alternatives likely involve higher costs or less direct routes, though the extended travel duration is a notable trade-off.