Start with the 17:30 LOT Polish Airlines flight from Istanbul to Düsseldorf, about 5h 30m. Transfer in Düsseldorf, then take the 07:30 (+1d) FlixBus bus on to Cologne (45 min). Transfer in Cologne Airport CGN, then take the 09:15 (+1d) FlixBus bus on to Maastricht (1h 35m). You arrive in Maastricht around 10:50 (+1d). In total it's roughly EUR 111 over 16h 47m, 3 transfers.
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Opens Omio — enter your date to compare trains and buses for this route; the price is finalised at checkout.
Fly into Düsseldorf, then continue to Maastricht by bus (45 min) — routing via Düsseldorf keeps the trip simple. Flight (LOT Polish Airlines, 5h 30min) + Bus (FlixBus, 45min) via Düsseldorf + Bus (FlixBus, 1h 35min) via Cologne Airport CGN.